It has been one year since the tragic explosion of Flight 180. While going on vacation, Kimberly Corman, (AJ Cook) traveling with her friend Shaina (Sarah Carter) and two other male friends, has a terrifying vision of a horrific car pile-up. She causes outrage when she blocks the on ramp to the highway, but the signs prove true. In a mental institution, she meets Clear Rivers (Ali Larter), the sole survivor of Flight 180, who has had similar experience with premonition. She reluctantly accepts Kim's offer to help her spot the signs to keep her and the others alive, but the deaths have already begun.